Grayscale Research Adds 6 Promising Altcoins to Its Top 20 List for 2025

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Grayscale Research has updated its "Top 20" list of high-potential crypto assets for Q1 2025, adding six new tokens: Hyperliquid (HYPE), Ethena (ENA), Virtual Protocol (VIRTUAL), Jupiter (JUP), Jito (JTO), and Grass. These projects represent cutting-edge innovations across decentralized finance (DeFi), AI, and infrastructure, reflecting Grayscale's focus on emerging blockchain trends.

New Additions: Innovation and Growth Potential

1. Hyperliquid (HYPE)

A Layer 1 blockchain gaining traction for its perpetuals decentralized exchange (DEX).

2. Ethena (ENA)

A DeFi protocol pioneering synthetic stablecoins with yield-generating mechanisms.

3. Virtual Protocol (VIRTUAL)

Develops decentralized AI agents on the Base blockchain, merging AI with Web3.

4. Jupiter (JUP) & Jito (JTO)

5. Grass

A decentralized data network offering alternatives to centralized cloud services.

👉 Explore Solana’s top DeFi projects

Selection Criteria: Rigorous Evaluation

Grayscale’s inclusion decisions are based on:

Key Themes for 2025

  1. DeFi & Tokenization: Expansion of decentralized financial tools.
  2. Decentralized AI: Projects like Virtual Protocol bridging AI and blockchain.
  3. Infrastructure Growth: Scalability solutions (e.g., Optimism for Ethereum) and DePIN (Helium).

Notable List Adjustments

👉 Why oracle networks matter in DeFi

FAQ

Q: Why did Grayscale add Grass to its Top 20?
A: Grass addresses demand for decentralized data solutions, a growing sector in Web3.

Q: How does Ethena’s stablecoin differ from traditional ones?
A: Ethena’s synthetic dollar (USDe) uses delta-neutral hedging to generate yield, unlike fiat-backed stablecoins.

Q: What makes Solana’s ecosystem stand out?
A: High throughput and low fees attract DeFi builders (e.g., Jito, Jupiter).

Q: Is Celo’s removal permanent?
A: Grayscale reassesses quarterly; Celo could re-enter if fundamentals improve.

Conclusion

Grayscale’s 2025 picks highlight innovation, infrastructure, and cross-sector synergies. With tokens like Virtual Protocol and Grass, the list underscores blockchain’s expansion beyond finance into AI and data.

👉 Discover more about Layer 1 blockchains


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